The Cole-Parmer TELOS PPT Protein Precipitation Columns, 1 mL (EW-06482-37) are individual dual-frit columns for cleaning up biological fluid samples, particularly plasma. The complete precipitation process takes place within the column, reducing the need for separate liquid-transfer and centrifugation steps.
Key Features
- Individual 1 mL column format, suited to small or varying numbers of biological fluid samples
- Specialised dual-frit construction, supporting efficient protein precipitation and subsequent filtrate collection
- Precipitation solvent retention, with one frit designed to hold acetonitrile within the column before sample addition
- Reduced risk of filter blockage, using a second frit with larger porosity to support filtrate collection
- Complete in-column processing, removing the need for separate offline liquid handling and centrifugation steps
- Designed for biological fluid cleanup, with plasma identified as a primary sample matrix
- Defined precipitation ratio, using an optimum acetonitrile-to-plasma ratio of 4:1 v/v
- Convenient pack of 100 columns, supporting routine laboratory sample-preparation workflows
Benefits
- Streamlines protein precipitation by combining solvent contact, precipitation and filtration within one column.
- Reduces manual sample transfers and eliminates the separate centrifugation stage described for conventional workflows.
- Promotes reproducible precipitation when the sample is dispensed directly into the acetonitrile using the recommended procedure.
- Helps produce precipitate-free filtrate through the complementary functions of the two fritted disks.
- Provides a practical column format for laboratories processing small batches or changing sample numbers.
Why Choose the Cole-Parmer TELOS PPT Protein Precipitation Columns, 1 mL (EW-06482-37)?
These TELOS PPT columns provide a compact dual-frit approach to plasma protein precipitation without separate offline transfer and centrifugation stages. John Morris Group can assist with product availability and the selection of related chromatography sample-preparation consumables.
