CEM Rink Amide ProTide Resin (LL), 1g, is an advanced resin designed for the synthesis of long and challenging peptide amides. The resin features an optimized PEG and polystyrene core, providing excellent swelling properties and a reliable environment for difficult peptide synthesis, even for sequences longer than 75 amino acids.
Product Features
- Rink Amide ProTide Resin (LL), 1g with PEG-PS core
- Ideal for long and difficult peptide sequences, >75 amino acids
- Loading: 0.15 – 0.25 mmol/g
- Optimized PEG and polystyrene core ensures excellent swelling and reaction efficiency
- Compatible with Liberty Blue microwave peptide synthesizer
- C-terminal amino acid reacts with linker-chloride in presence of KI, DIEA, and microwave irradiation
- Stable towards hydrolysis during storage and handling
- Hyperacid-sensitive TCP(Cl) minimizes diketopiperazine and 3-(1-piperidinyl)alanine formation
- Eliminates need for multiple pre-loaded acid-linked resins
- References: Sandhya K., Ravindranath B., Tetrahedron Lett. 49, 2435 2008; Heinlein C., Silva D., Tröster A., Angew. Chem. 50, 6406 2011
Key Advantages
- Automated, high-temperature loading in 10 minutes
- Reduces epimerization and dipeptide formation during loading
- Reliable for routine synthesis of long, difficult peptides
- Strong stability and reproducibility in peptide synthesis workflows
Benefits
- Supports synthesis of complex peptide sequences with high yield
- Maintains consistent peptide quality for research and production
- Easy integration into automated peptide synthesis systems
- Minimizes handling errors and storage concerns
Why Choose CEM Rink Amide ProTide Resin (LL)), 1g?
This resin offers a robust, high-performance solution for the synthesis of challenging peptide amides, ensuring excellent results for both routine and complex peptide sequences.
