Spex SamplePrep · Tissue Homogenizer

Fast, reproducible cell lysis with the Spex HG-400 MiniG

Automated bead-beating homogenisation in roughly one to two minutes.
The compact Spex 1600 SamplePrep HG-400 MiniG disrupts tissues and lyses cells through a powerful vertical bead-beating motion - built for high-throughput DNA/RNA, protein and pesticide-residue sample preparation.

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Why the Spex HG-400 MiniG?

High-throughput

Process a range of vials or up to two deep-well titer plates in a single run to keep busy labs moving.

Reproducible results

Mechanical bead beating removes the operator-to-operator variability of manual grinding.

Fast turnaround

Most samples are homogenised in roughly one to two minutes, with or without buffer.

Adjustable clamp

Secures containers from 2 mL to 50 mL - no extra fittings needed to switch sample sizes.

Operator safety

A lid interlock stops the motor instantly if the lid is opened during grinding.

Cryo-ready

Optional Kryo-Tech accessories enable cold grinding to preserve temperature-sensitive RNA and proteins.

The Instrument

Spex 1600 SamplePrep HG-400 MiniG

Spex 1600 SamplePrep HG-400 MiniG homogenizer, front view

Bead-Beating Homogenizer

Spex HG-400 MiniG

A small-footprint tissue homogenizer and cell lyser that uses vertical bead beating to disrupt cells and tissues quickly and consistently - with a clear lid window for monitoring each run.

–Sample range: 2 mL to 50 mL vials, or up to two deep-well titer plates
–Fast processing: homogenises most samples in roughly 1-2 minutes
–Adjustable rate and timer with an LCD run-time display in min:sec
–115V/60Hz & 230V/50Hz, CE approved; optional Kryo-Tech cryogenic accessories

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Designed for the bench

Simple controls, built-in protection

–Load samples, set time and speed, press start - straightforward operation for any user.
–A window in the lid lets you watch the grinding process in real time.
–Lid safety interlock stops the motor the moment the lid is opened mid-run.
–LCD display tracks run times in minute:second format for consistent protocols.
–Compact footprint frees up bench space without sacrificing grinding power.

Spex HG-400 MiniG homogenizer showing lid, clamp and control panel

Applications

Where the HG-400 MiniG performs

Tissue Homogenisation Disrupt animal and plant tissue ready for downstream analysis.

DNA / RNA Extraction Release nucleic acids quickly for molecular biology workflows.

Protein Extraction Recover proteins and metabolites from lysed cells.

Cell Lysis Break open yeast, bacteria and cultured cells efficiently.

Pesticide Residue Prepare samples for QuEChERS and SweEt extraction methods.

Biofuel Research Process seeds, stems, roots and leaves for analysis.

Cannabis & Botanicals Homogenise fruit, seeds and plant material consistently.

Cryogenic Grinding Pair with Kryo-Tech to grind heat-sensitive samples cold.

Interested in the Spex HG-400 MiniG?

Talk to our sample-preparation specialists about configuring the right MiniG setup, grinding vials and Kryo-Tech accessories for your lab.

Call 1300 501 555 or email info@johnmorrisgroup.com. Prices in AUD include GST.

Spex HG-400 MiniG Tissue Homogenizer