The HiScreen MabSelect SuRe Column, 1 x 4.7 mL (28926977) is a prepacked protein A affinity chromatography column for monoclonal antibody capture during process development. The column is packed with MabSelect SuRe resin in a 4.7 mL HiScreen format for method optimisation, parameter screening, and scale-up studies.
Key Features
- Prepacked HiScreen column format, supplied as 1 x 4.7 mL for convenient process development workflows
- MabSelect SuRe protein A affinity resin, designed for capture of monoclonal antibodies at process scale
- Alkali-stabilised protein A ligand, supporting cleaning-in-place with 0.1 to 0.5 M sodium hydroxide
- 4.7 mL column volume, with 0.77 x 10 cm column dimensions for process-relevant method work
- Highly cross-linked agarose matrix, with spherical particles and a median particle size of approximately 85 µm
- Defined binding capacity, approximately 141 mg human IgG per column according to Cytiva selection guidance
- Recommended resin flow velocity, specified at 100 to 500 cm/h with a recommended maximum operating flow velocity of 500 cm/h
- Biocompatible polypropylene column body, with a column hardware pressure limit of 8 bar, 0.8 MPa, 117 psi
Benefits
- Supports method optimisation and parameter screening for monoclonal antibody capture workflows.
- Helps reduce sample and buffer consumption while maintaining a process-relevant 10 cm bed height.
- Can be connected in series with a union when a 20 cm bed height is required for further method work.
- Provides a ready-to-use format for evaluating MabSelect SuRe resin before scale-up to larger chromatography formats.
- Supports process development studies using an alkali-resistant protein A capture resin.
Why Choose the HiScreen MabSelect SuRe Column, 1 x 4.7 mL (28926977)?
The HiScreen MabSelect SuRe Column, 1 x 4.7 mL (28926977) is suited to laboratories developing and optimising protein A affinity capture methods for monoclonal antibodies. John Morris Group supplies Cytiva chromatography columns to support antibody purification and process development workflows across Australian laboratories.
