The HiTrap MabSelect PrismA X Column, 1 x 1 mL (17550151), is a prepacked protein A affinity chromatography column for monoclonal antibody capture. It contains MabSelect PrismA X resin, a high-capacity protein A resin designed for efficient mAb capture with strong alkaline stability for repeated cleaning-in-place workflows.
Key Features
- Prepacked 1 x 1 mL HiTrap format, supplied for small-scale antibody capture, method development and rapid screening workflows
- MabSelect PrismA X protein A resin, designed for high-capacity capture of monoclonal antibodies
- Alkali-stable protein A-derived ligand, produced from E. coli and immobilised by single-point attachment
- Highly cross-linked agarose matrix, supplied as spherical resin with an approximate 50 µm median particle size
- High dynamic binding capacity, with more than 80 mg mAb/mL resin at 6 min residence time and more than 74 mg mAb/mL resin at 4 min residence time
- Short bed height capability, supporting rapid cycling chromatography approaches for improved productivity in the protein A capture step
- Defined pH stability, with pH 3 to 12 operational stability and pH 2 to 14 cleaning-in-place stability
- NaOH-compatible CIP stability, specified for 0.5 to 1.0 M sodium hydroxide cleaning conditions
Benefits
- Supports efficient capture of monoclonal antibodies during affinity chromatography development.
- Helps reduce resin and buffer consumption in suitable high-titre mAb capture workflows.
- Provides a convenient prepacked format for early testing before moving to larger column formats.
- High alkaline stability supports repeated cleaning-in-place during robust purification development.
- Short bed height compatibility helps laboratories evaluate rapid cycling chromatography strategies.
Why Choose the HiTrap MabSelect PrismA X Column, 1 x 1 mL (17550151)?
Choose the HiTrap MabSelect PrismA X Column, 1 x 1 mL (17550151), when you need a compact prepacked protein A column for high-capacity monoclonal antibody capture and process development. John Morris Group can supply this MabSelect chromatography product for Australian laboratories working with antibody purification and affinity capture workflows.
