The MabSelect HiTrap SuRe 70 Protein A Column, 5 x 5 mL (17542414) is a pack of five 5 mL prepacked HiTrap columns containing MabSelect SuRe 70 protein A resin. It is designed for high dynamic binding capacity and cost-efficient capture of monoclonal antibodies, especially where strong productivity is needed at shorter residence times.
Key Features
- Prepacked HiTrap column format, supplied as five 5 mL columns for convenient mAb capture method development and scale-up work
- High dynamic binding capacity, with DBC above 70 mg mAb/mL resin at 6 min residence time
- Strong short-residence-time performance, with DBC above 65 mg mAb/mL resin at 4 min residence time
- Highly cross-linked agarose matrix, using a spherical high-flow base matrix for mAb capture workflows
- Alkali-stable protein A-derived ligand, produced in E. coli and coupled by single-point attachment
- 50 µm median particle size, supporting efficient mass transfer and packed-bed chromatography performance
- Recommended maximum flow velocity up to 400 cm/h, based on operation at 10 cm bed height
- Robust alkaline cleaning compatibility, with CIP stability in 0.1 to 0.5 M NaOH
Benefits
- Supports cost-efficient capture of monoclonal antibodies where a limited number of resin cycles is expected.
- Helps improve resin utilisation through high binding capacity at practical residence times.
- Provides five ready-to-use 5 mL HiTrap columns for parallel screening, repeat runs or method development.
- Enables productive short-bed-height workflows, including rapid cycling chromatography applications.
- Supports robust cleaning strategies that help reduce bioburden risk during mAb processing.
Why Choose the MabSelect HiTrap SuRe 70 Protein A Column, 5 x 5 mL (17542414)?
The MabSelect HiTrap SuRe 70 Protein A Column, 5 x 5 mL (17542414) gives Australian laboratories a convenient prepacked format for evaluating high DBC protein A capture of monoclonal antibodies. John Morris Group supplies Cytiva chromatography products with local support to help match column format, process scale and purification workflow to your application.
