The MabSelect HiTrap SuRe 70 Column, 5 x 1 mL (17542412) is a pack of prepacked HiTrap columns containing MabSelect SuRe 70 protein A resin for monoclonal antibody capture. The resin combines high dynamic binding capacity with an alkali-stable protein A-derived ligand, supporting efficient mAb purification workflows where productivity and cleaning stability are important.
Key Features
- Prepacked 5 x 1 mL HiTrap format, supplied as five ready-to-use columns for small-scale mAb capture and process development
- High dynamic binding capacity, with QB10% above 70 mg mAb/mL resin at 6 min residence time and above 65 mg mAb/mL resin at 4 min residence time
- Alkali-stable protein A ligand, using a protein A-derived ligand from E. coli for robust antibody affinity capture
- Highly cross-linked agarose matrix, with a spherical matrix and 50 µm median particle size
- Designed for short bed heights, supporting rapid cycling chromatography and high-productivity protein A capture workflows
- Strong pressure-flow performance, with recommended maximum operating flow velocities of 220 cm/h at 20 cm bed height and 400 cm/h at 10 cm bed height
- Broad pH stability, with operational pH stability from 3 to 12 and CIP pH stability from 2 to 13.7
- CIP-compatible resin chemistry, with CIP stability from 0.1 to 0.5 M NaOH
Benefits
- Supports efficient monoclonal antibody capture where high binding capacity and short residence times are required.
- Reduces the need for in-house column packing during screening, method development and small-scale purification work.
- Helps improve productivity in rapid cycling chromatography workflows using short bed heights.
- Supports robust cleaning strategies for protein A chromatography workflows where alkaline CIP is required.
Why Choose the MabSelect HiTrap SuRe 70 Column, 5 x 1 mL (17542412)?
The MabSelect HiTrap SuRe 70 Column, 5 x 1 mL (17542412) is a practical choice for laboratories developing high-productivity antibody capture methods using MabSelect SuRe 70 protein A resin. John Morris Group supplies Cytiva chromatography products to Australian laboratories, helping researchers source verified consumables for mAb purification and process development.
