HiTrap Capto adhere Columns, 5 × 5 mL (Part Number 28405846) are supplied as five prepacked 5 mL chromatography columns containing Capto adhere resin. They are designed for post-protein A polishing of monoclonal antibodies, using multimodal strong anion exchange functionality to support contaminant removal in flow-through purification workflows.
Key Features:
- Five prepacked 5 mL columns, providing a practical format for chromatography method development and small-scale purification workflows.
- Multimodal strong anion exchange functionality, combining ionic, hydrogen bonding, and hydrophobic interactions for selectivity different from conventional anion exchangers.
- Capto adhere chromatography resin, based on a highly cross-linked, spherical agarose matrix.
- Defined flow-rate guidance, with a recommended flow rate of 5 mL/min and a maximum flow rate of 20 mL/min.
- Regular-use pH range of 3 to 12, supporting defined operating conditions for Capto adhere chromatography workflows.
- Approximately 75 µm particle size, specified as the median particle size of the cumulative volume distribution.
- Post-protein A polishing use, designed for removal of process-related contaminants while the target monoclonal antibody passes through the column.
Benefits
- Supports a streamlined polishing step following protein A capture during monoclonal antibody purification.
- Helps reduce leached protein A, aggregates, host cell proteins, nucleic acids, and viruses in suitable purification workflows.
- Provides a ready-to-use prepacked format for screening loading conditions and optimising purification methods.
- Supplies five matching columns for comparative runs, repeat processing, or process-screening activities.
Why Choose the HiTrap Capto adhere Columns, 5 × 5 mL (Part Number 28405846)?
HiTrap Capto adhere Columns provide a convenient 5 mL prepacked format for post-protein A monoclonal antibody polishing and multimodal contaminant-removal workflows. John Morris Group can supply this exact five-column pack for laboratories developing or optimising Capto adhere purification methods.
