The Capto MMC Multimodal Chromatography Resin, 25 mL (17531710) is a salt-tolerant multimodal weak cation exchange resin for protein purification. This 25 mL pack uses a highly cross-linked agarose matrix with multimodal ligand functionality, enabling protein binding at high conductivity and providing selectivity different from traditional ion exchangers.
Key Features
- Salt-tolerant multimodal cation exchange resin, designed to bind proteins at the conductivity of the feed material
- Different selectivity from traditional ion exchangers, using ionic, hydrogen bonding, and hydrophobic interaction mechanisms
- Highly cross-linked agarose matrix, providing a rigid spherical base for high flow processing
- Ionic capacity of 0.07 to 0.09 mmol H+ per mL resin, supporting multimodal weak cation exchange behaviour
- Approximately 75 µm particle size, based on the d50v median particle size of the cumulative volume distribution
- High dynamic binding capacity, with at least 45 mg BSA per mL resin at 30 mS/cm under stated test conditions
- Large-scale pressure and flow capability, with at least 600 cm/h at no more than 0.3 MPa under stated large-scale conditions
- Broad operating stability, with operational pH stability from 3 to 12 and cleaning-in-place pH stability from 3 to 14
Benefits
- Allows direct processing of clarified feedstocks in many cases without prior dilution to reduce conductivity.
- Supports capture and intermediate purification of proteins from large feed volumes.
- Helps increase productivity through high dynamic binding capacity at high conductivity.
- Provides useful method development flexibility across pH, conductivity, and elution conditions.
- Can reduce process time through high volume throughput and high flow operation.
Why Choose the Capto MMC Multimodal Chromatography Resin, 25 mL (17531710)?
The Capto MMC Multimodal Chromatography Resin, 25 mL (17531710) is suited to laboratories developing protein purification processes that need salt-tolerant binding and selectivity beyond standard ion exchange resins. John Morris Group supplies Cytiva chromatography resins across Australia, helping laboratories source verified consumables for process development and biopurification workflows.
