The Capto MMC Multimodal Resin, 100 mL (17531702) is a salt-tolerant multimodal weak cation exchange chromatography resin for protein purification at high and low ionic strengths. It uses a highly cross-linked agarose matrix with a carboxylic acid ligand, offering different selectivity compared with traditional ion exchangers.
Key Features
- 100 mL Capto MMC resin pack, supplied for multimodal chromatography process development and purification workflows
- Multimodal weak cation exchange chemistry, combining ionic, hydrogen bonding, and hydrophobic interaction modes
- Salt-tolerant binding behaviour, allowing proteins to bind at the conductivity of the feed material
- Highly cross-linked spherical agarose matrix, supporting high-flow processing with low backpressure
- Approximately 75 µm median particle size, supporting packed-bed chromatography operation
- 0.07 to 0.09 mmol H+/mL resin ionic capacity, supporting multimodal cation exchange performance
- At least 45 mg BSA/mL resin dynamic binding capacity, measured at 30 mS/cm under stated test conditions
- At least 600 cm/h pressure/flow performance, at no more than 0.3 MPa in the stated column and buffer conditions
Benefits
- Helps increase productivity by supporting protein binding at high conductivity.
- Can reduce the need for feed dilution before loading in suitable purification processes.
- Provides selectivity that differs from traditional ion exchangers, helping solve challenging separations.
- Supports high-volume throughput for faster processing in process development and scale-up workflows.
- Helps reduce unit operation size where high binding capacity and throughput are suitable for the process.
Why Choose the Capto MMC Multimodal Resin, 100 mL (17531702)?
The Capto MMC Multimodal Resin, 100 mL (17531702) is suited to laboratories and bioprocess teams needing a salt-tolerant multimodal resin for capture and intermediate purification of proteins. John Morris Group supplies chromatography resins and consumables for Australian laboratories, with support for selecting suitable purification workflow components.
