Capto MMC ImpRes Chromatography Resin, 100 mL (17371602) is a bulk multimodal chromatography resin for high-resolution polishing of monoclonal antibodies and other biomolecules. It combines a high-flow agarose matrix with a multimodal weak cation exchanger ligand for selective polishing across a broad operating window.
Key Features
- 100 mL bulk resin format, supplied as Capto MMC ImpRes for packing into suitable chromatography columns
- High-resolution polishing design, with small 36-44 µm beads for improved polishing performance
- High-flow agarose matrix, providing the rigid base matrix used for Capto MMC ImpRes resin
- Multimodal weak cation exchanger ligand, enabling ionic, hydrogen bonding, hydrophobic, and thiophilic interactions
- High mAb binding capacity, with 60 to 90 mg mAb/mL chromatography resin at 4 to 5 min residence time
- Broad pH stability, with a working range of pH 3 to 12 and CIP range of pH 2 to 14
- Robust chemical stability, compatible with commonly used aqueous buffers and selected cleaning agents including 1 M NaOH
- Scalable chromatography use, suitable for use with modern chromatography equipment from laboratory to production scale
Benefits
- Supports selective polishing of mAbs after protein A capture while helping retain product yield.
- Helps process developers screen and optimise pH and conductivity conditions for challenging biomolecules.
- Allows loading at moderate salt levels, reducing the need for dilution after the protein A step.
- Can support smaller elution pool volumes and reduced buffer consumption in polishing workflows.
- Provides a bulk resin option for laboratories moving from method development toward scalable purification.
Why Choose the Capto MMC ImpRes Chromatography Resin, 100 mL (17371602)?
Capto MMC ImpRes Chromatography Resin, 100 mL (17371602) is suited to laboratories developing high-resolution multimodal polishing steps for mAbs, antibody fragments, and other biomolecules. John Morris Group supplies Capto chromatography resins to support Australian laboratories with process development, optimisation, and scale-up workflows.
