Capto MMC ImpRes Multimodal Chromatography Resin, 25 mL (17371601) is a BioProcess mixed-mode chromatography resin for high-resolution polishing of monoclonal antibodies and other biomolecules. It uses a multimodal weak cation exchanger ligand on a high-flow agarose matrix, supporting selective impurity removal across a broad pH and salt operating window.
Key Features
- 25 mL bulk resin format, supplied under Cytiva product code 17371601 for process development and polishing work
- Multimodal weak cation exchanger ligand, providing selectivity through multiple interaction modes
- High-flow agarose matrix, supporting pressure-flow performance for chromatography process development
- Small particle resin, with 36 to 44 µm d50V average particle size for high-resolution polishing
- High mAb binding capacity, specified at 60 to 90 mg mAb/mL chromatography resin at 4 to 5 min residence time
- Defined ionic capacity, specified at 25 to 39 µmol/mL
- Broad operating pH range, with working stability from pH 3 to 12
- CIP-compatible pH stability, with cleaning-in-place stability from pH 2 to 14
Benefits
- Supports high-resolution polishing after protein A capture in monoclonal antibody purification workflows.
- Helps remove aggregates, host cell proteins and other key contaminants while maintaining useful yield.
- Provides multimodal selectivity for challenging purification problems where traditional ion exchange may not be enough.
- Allows pH and conductivity screening during process development to optimise binding and impurity removal.
- Supports a platform approach to mAb process development using Cytiva Capto mixed-mode resin chemistry.
Why Choose the Capto MMC ImpRes Multimodal Chromatography Resin, 25 mL (17371601)?
Choose Capto MMC ImpRes Multimodal Chromatography Resin, 25 mL (17371601) when you need a verified Cytiva resin for high-resolution mAb polishing, aggregate removal and multimodal method development. John Morris Group supplies Cytiva chromatography products across Australia and can help confirm ordering details for this part.
