HiScreen Capto adhere ImpRes Prepacked Column, 4.7 mL (17371520) is a ready-to-use chromatography column prepacked with BioProcess Capto adhere ImpRes resin. It is designed for method optimisation and parameter screening in multimodal chromatography workflows, particularly for high-resolution polishing of monoclonal antibodies and other biomolecules.
Key Features
- Ready-to-use HiScreen format, supplied as 1 × 4.7 mL prepacked column for convenient screening work
- BioProcess Capto adhere ImpRes resin, using strong anion exchange multimodal chemistry for differentiated selectivity
- 10 cm bed height, supporting method optimisation and parameter screening on the HiScreen platform
- Defined loading range, with a typical loading range of 225-425 mg mAb per column
- Screening flow rate range, with 1.2 mL/min recommended and 2.3 mL/min maximum flow rate
- Fine particle resin, with 36-44 µm d50V particle size for high-resolution polishing
- Designed for contaminant removal, supporting efficient removal of aggregates, viruses, DNA, host cell proteins and leached protein A in mAb processes
Benefits
- Helps laboratories screen polishing conditions using a compact prepacked column before scaling to larger chromatography formats.
- Supports high-resolution monoclonal antibody polishing in the second or third purification step downstream of protein A capture.
- Provides multimodal selectivity that can help optimise separations where traditional ion exchange chemistry is not sufficient.
- Reduces column packing work during method development and supports more reproducible screening runs.
- Allows scale-up to BioProcess columns packed with the same chromatography resin using the same linear fluid velocity.
Why Choose the HiScreen Capto adhere ImpRes Prepacked Column, 4.7 mL (17371520)?
Choose the HiScreen Capto adhere ImpRes Prepacked Column, 4.7 mL (17371520) when you need a verified Cytiva column for Capto adhere ImpRes method screening and mAb polishing development. John Morris Group supplies Cytiva chromatography products across Australia and can help confirm ordering details for this part.
