CEM Rink Amide ProTide Resin (LL), 25g, is a high-performance resin ideal for synthesizing long and challenging peptide amides. With an optimized PEG and polystyrene core, this resin offers excellent swelling properties and a stable environment for peptide synthesis, even for sequences longer than 75 amino acids.
Product Features
- Rink Amide ProTide Resin (LL), 25g with PEG-PS core
- Designed for long and difficult peptide sequences, >75 amino acids
- Loading: 0.15 – 0.25 mmol/g
- Optimized PEG and polystyrene core ensures excellent swelling and reaction efficiency
- Compatible with Liberty Blue microwave peptide synthesizer
- C-terminal amino acid reacts with linker-chloride in presence of KI, DIEA, and microwave irradiation
- Stable towards hydrolysis during storage and handling
- Hyperacid-sensitive TCP(Cl) minimizes diketopiperazine and 3-(1-piperidinyl)alanine formation
- Eliminates need for multiple pre-loaded acid-linked resins
- References: Sandhya K., Ravindranath B., Tetrahedron Lett. 49, 2435 2008; Heinlein C., Silva D., Tröster A., Angew. Chem. 50, 6406 2011
Key Advantages
- Automated, high-temperature loading completes in 10 minutes
- Reduces epimerization and dipeptide formation during loading
- Reliable for routine synthesis of long, difficult peptides
- Strong stability and reproducibility in peptide synthesis workflows
Benefits
- Supports synthesis of complex peptide sequences with high yield
- Maintains consistent peptide quality for research and production
- Easy integration into automated peptide synthesis systems
- Minimizes handling errors and storage concerns
Why Choose CEM Rink Amide ProTide Resin (LL), 25g?
This resin provides a robust, high-performance solution for the synthesis of challenging peptide amides, ensuring excellent results for both routine and complex peptide sequences.
